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Longevity's secrets sought in DNA of 100-year-olds

New York (ap)-George hart's "107 last month, scientists want to know how he and other older folks like him so far. So his hand than some of his DNA. His 100 centenarians take announced on Wednesday, will examine some of the latest scientific tools and one of the oldest of citizens of a part of the project: whole genome sequencing, crack a complete set of a person's DNA.
Scientists think, very old healthy human DNA can provide clues, how they live so long. This may one day be drugs to help us stay longer rest without disease.
You reach, say, 105 time, "it is hard to get have a certain genetic advantage, dr. Thomas said:" Pierce, Boston university of older epidemiology experts.
Pierce is to help find the X prize competition consul gene centenarians. X prize foundation, space is famous for its competition, is to provide a bonus of 100000 dollars, the researchers crack from 100 more than 100 above the complete DNA code. This contest will judge the accuracy, completeness and sequencing speed and cost.
This contest is a reboot and old new focus of competition for over years old, and it's the second sequencing project involves announced this month old man.
Genome pioneer Craig venter, said-year-old project just in reveals an longevity and health of the genetic secrets of the first step.
"We need 10000 genome, not 100, start to understand the disease and the health of the contact between genetics,," Mr Venter, said who is common host X prize competition.
Chester's "107, hart, New Jersey, play and teach tennis until he was 94. He said he took part in the X prize project, because he was interested in science and technology. It was not clear his gene can reveal too much. No one in his family as reached 100, he believes that only a couple of up to 90, he said in a telephone interview.
So, why does he think he lived so long? He believes that his wife, Mary 70 years of marriage. She and he was quoted "in so much interest in" for life, from construction as a pursuit in the electronic research career children the radio.
But scientists believe it has more, they wish to use genome sequencing in the investigation. The university of Utah, who is seeking through other means longevity genes Richard Cawthon doctor says, it might become genetic characteristics, protection, prevention DuoZhong disease or slow the process of general aging.
NIR Barzilai Einstein medical college in New York, he said, a-year-old DNA of the protection function, can overcome even less than ideal way of life. His own study found that-year-old how life, "as a group, they didn't do the right thing."
Many of his group obese or overweight. Many smokers, and several exercise or follow a vegetarian diet. He's the most ancient of participants, who died just her the 110th this month for the 95 smoked.
"Her genes to the protection of the environment, she said, Barzilai." One of her sisters died, at the age of 102, and her brother is one of 105, still management hedge funds.
Earlier this month, San Diego the Scripps health announced that different genome project, involving the old man. The Scripps research Wellderly received 1000 80 years old, from the sequencing the entire genome of the old company.
A complete genome found that not only gene, but there are other genes responsible for regulation of the DNA. It's "the MengDi", showing the DNA molecular disease and the health of the key, dr Eric said: "the alamo, who is responsible for the Wellderly research.
The participants in the study, the average age for the 87 and range up to 108, they never diabetes, heart disease or cancer, or any disease of the nervous system.
"Why these people teflon coating?" The alamo asked. "Why not make their disease?"
Turns out a lot of the complete genome of power is in trying to find out the "new new thing," he said.
"There have been too much emphasis on its obstacle, and not enough particularly healthy person", learning their genome, poplars said. "Now we have a powerful tool to do this."




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